Article
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa.
Nature genetics - 1 May 2003
Tamaru Hisashi, Zhang Xing, McMillen Debra, Singh Prim B, Nakayama Jun-ichi, Grewal Shiv I, Allis C David, Cheng Xiaodong, Selker Eric U
Abstract excerpt
Besides serving to package nuclear DNA, histones carry information in the form of a diverse array of post-translational modifications. Methylation of histones H3 and H4 has been implicated in long-term epigenetic 'memory'. Dimethylation or trimethylation of Lys4 of histone H3 (H3 Lys4) has been found in expressible euchromatin of yeasts and mammals. In contrast, methylation of Lys9 of histone H3 (H3 Lys9) has...
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