Genome quality control: RIP (repeat-induced point mutation) comes to Podospora.

doi:10.1046/j.1365-2958.2001.02367.x

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Article

Genome quality control: RIP (repeat-induced point mutation) comes to Podospora.

Molecular microbiology - 1 May 2001

Graïa F, Lespinet O, Rimbault B, Dequard-Chablat M, Coppin E, Picard M

Abstract excerpt

RIP (repeat-induced point mutation) is a silencing process discovered in Neurospora crassa and so far clearly established only in this species as a currently occurring process. RIP acts premeiotically on duplicated sequences, resulting in C-G to T-A mutations, with a striking preference for CpA/TpG dinucleotides. In Podospora anserina, an RIP-like event was observed after several rounds of sexual reproduction in...

Topics

Ascomycota
DNA Methylation
Genome, Fungal
Phenotype
Point Mutation
Tandem Repeat Sequences

Source

Open in PubMed

Identifiers

PMID: 11359565
DOI: 10.1046/j.1365-2958.2001.02367.x

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