Article
Methylation of histone H3 lysine 36 is required for normal development in Neurospora crassa.
Eukaryotic cell - 1 Aug 2005
Adhvaryu Keyur K, Morris Stephanie A, Strahl Brian D, Selker Eric U
Abstract excerpt
The SET domain is an evolutionarily conserved domain found predominantly in histone methyltransferases (HMTs). The Neurospora crassa genome includes nine SET domain genes (set-1 through set-9) in addition to dim-5, which encodes a histone H3 lysine 9 HMT required for DNA methylation. We demonstrate that Neurospora set-2 encodes a histone H3 lysine 36 (K36) methyltransferase and that it is essential for normal...
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