Article
Environmental regulation of Salmonella typhi invasion-defective mutants.
Infection and immunity - 1 Feb 1998
Leclerc G J, Tartera C, Metcalf E S
Abstract excerpt
Salmonella typhi is the etiologic agent of human typhoid. During infection, S. typhi adheres to and invades epithelial and M cells that line the distal ileum. To survive in the human host, S. typhi must overcome numerous complex extracellular and intracellular environments. Since relatively little is known about S. typhi pathogenesis, studies were initiated to identify S. typhi genes involved in the early steps...
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