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Article

Molecular genetic analysis of the Escherichia coli phoP locus.

Journal of bacteriology - 1 Jan 1992

Groisman E A, Heffron F, Solomon F

Abstract excerpt

We have cloned the Escherichia coli phoP gene, a member of the family of environmentally responsive two-component systems, and found its deduced amino acid sequence to be 93% identical to that of the Salmonella typhimurium homolog, which encodes a major virulence regulator necessary for intramacrophage survival and resistance to cationic peptides of phagocytic cells. The phoP gene was mapped to kilobase 1202 on...

Topics

Amino Acid Sequence
Bacterial Proteins
Bacteriophage mu
Base Sequence
Cloning, Molecular
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Molecular Sequence Data
Mutation
Phenotype
Replicon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Restriction Mapping

Sequence Homology, Nucleic Acid

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 1530848
DOI: 10.1128/jb.174.2.486-491.1992
PMCID: PMC205741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1530848-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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