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Article

Molecular genetic analysis of the Escherichia coli phoP locus.

Journal of bacteriology - 1 Jan 1992

Groisman E A, Heffron F, Solomon F

Abstract excerpt

We have cloned the Escherichia coli phoP gene, a member of the family of environmentally responsive two-component systems, and found its deduced amino acid sequence to be 93% identical to that of the Salmonella typhimurium homolog, which encodes a major virulence regulator necessary for intramacrophage survival and resistance to cationic peptides of phagocytic cells. The phoP gene was mapped to kilobase 1202 on...

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Identifiers

PMID: 1530848
DOI: 10.1128/jb.174.2.486-491.1992
PMCID: PMC205741

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