Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic changes during the multistage pathogenesis of human papillomavirus positive and negative vulvar carcinomas.

Journal of the Society for Gynecologic Investigation - 1 Jan 2000

Flowers L C, Wistuba I I, Scurry J, Muller C Y, Ashfaq R, Miller D S, Minna J D, Gazdar A F

Abstract excerpt

OBJECTIVE: To identify the molecular alterations found in 30 human papillomavirus (HPV) positive (n = 15) and negative (n = 15) vulvar carcinomas (VC) and their associated preinvasive lesions (VIN [vulvar intraepithelial neoplasia]) and normal epithelium to determine a common molecular pathogenesis of HPV positive and negative VC. METHODS: Loss of heterozygosity (LOH) at seven 3p chromosomal regions (3p12,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Basal Cell
Share to Carcinoma in Situ

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 13

Share to Chromosomes, Human, Pair 17

Share to Chromosomes, Human, Pair 3

Share to Loss of Heterozygosity

Share to Papillomaviridae

Share to Vulvar Neoplasms

Source

Identifiers

PMID: 10486784
DOI: 10.1016/s1071-5576(99)00023-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic changes during the multistage pathogenesis of human papillomavirus positive and negative vulvar carcinomas.PMID 10486784Read ↗

Genomic Characterization of Vulvar (Pre)cancers Identifies Distinct Molecular Subtypes with Prognostic Significance.Semantic proximity Read ↗

Molecular events in the pathogenesis of vulvar squamous cell carcinoma.Semantic proximity Read ↗

Genetic abnormalities and HPV status in cervical and vulvar squamous cell carcinomas.Semantic proximity Read ↗

High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia.Semantic proximity Read ↗

CDKN2A(p16) and HRAS are frequently mutated in vulvar squamous cell carcinoma.Semantic proximity Read ↗

Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer.Semantic proximity Read ↗

Mutational signatures and chromosome alteration profiles of squamous cell carcinomas of the vulva.Semantic proximity Read ↗

Genetic alterations during the progression of squamous cell carcinomas of the uterine cervixSemantic proximity Read ↗

Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma.Semantic proximity Read ↗

Genetic aberrations detected by comparative genomic hybridisation in vulvar cancersSemantic proximity Read ↗

Comparative molecular profiling of HPV-induced squamous cell carcinomas.Semantic proximity Read ↗

Differentiated vulvar intraepithelial neoplasia contains Tp53 mutations and is genetically linked to vulvar squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.