Article
NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80.
The Journal of experimental medicine - 1 Oct 1994
Cella M, Longo A, Ferrara G B, Strominger J L, Colonna M
Abstract excerpt
Natural killer (NK) cell clones have been previously described which are inhibited by HLA-C alleles with Asn77-Lys80 (NK1-specific cells) or by HLA-C alleles with Ser77-Asn80 (NK2-specific cells). In the present work, the generation of NK cells with HLA-B-related specificities was attempted by st...
Topics
- Alleles
- Base Sequence
- Cytotoxicity, Immunologic
- Genes, MHC Class I
- HLA-B Antigens
- Humans
- Isoleucine
- Killer Cells, Natural
- Molecular Sequence Data
- Sensitivity and Specificity