Article
KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2005
Carr William Henry, Pando Marcelo Jorge, Parham Peter
Abstract excerpt
The killer cell Ig-like receptor (KIR) gene family encodes MHC class I receptors expressed by NK cells and several T cell subpopulations. Factors contributing to human KIR haplotype diversity are differences in gene number, gene content, and allelic polymorphism. Whereas functional and clinical consequences of the first two factors are established, knowledge of the effects of KIR gene polymorphism is limited to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
