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Article

C/EBP beta regulation of the tumor necrosis factor alpha gene.

The Journal of clinical investigation - 1 Oct 1994

Pope R M, Leutz A, Ness S A

Abstract excerpt

Activated macrophages contribute to chronic inflammation by the secretion of cytokines and proteinases. Tumor necrosis factor alpha (TNF alpha) is particularly important in this process because of its ability to regulate other inflammatory mediators in an autocrine and paracrine fashion. The mechanism(s) responsible for the cell type-specific regulation of TNF alpha is not known. We present data to show that the...

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Identifiers

PMID: 7929820
DOI: 10.1172/JCI117482
PMCID: PMC295278

Genes

EBP
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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