Article
NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.
The Journal of biological chemistry - 6 May 1994
Cheng Q, Cant C A, Moll T, Hofer-Warbinek R, Wagner E, Birnstiel M L, Bach F H, de Martin R
Abstract excerpt
Stimulation of endothelial cells by cytokines and bacterial lipopolysaccharide leads to activation of the transcription factor NF-kappa B. NF-kappa B in turn regulates the expression of several genes involved in the inflammatory reaction, including cell adhesion molecules, interleukins, and trans...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cells, Cultured
- DNA-Binding Proteins
- Endothelium, Vascular
- I-kappa B Proteins
- Lipopolysaccharides
- Molecular Sequence Data
- Mutation
- NF-KappaB Inhibitor alpha
- NF-kappa B
- Oligodeoxyribonucleotides
- Promoter Regions, Genetic
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-rel
- Sequence Deletion