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Article

Regulation of Interleukin-8 Gene Expression

1 May 1999

Abstract excerpt

Interleukin-8 (IL-8), a member of the CXC chemokine family, is an important activator and chemoattractant for neutrophils and has been implicated in a variety of inflammatory diseases. IL-8 is secreted in a stimulus-specific manner by a wide variety of cell types and is regulated primarily at the level of gene transcription. Functional studies indicate that IL-8 transcriptional responses to proinflammatory...

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PMID: 10386854
DOI: 10.1089/107999099313866

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