Article
Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model.
The Journal of clinical investigation - 1 Oct 1994
West D B, Goudey-Lefevre J, York B, Truett G E
Abstract excerpt
Loci linked to sensitivity to dietary obesity were identified by Quantitative Trait Locus (QTL) analysis of two mapping populations derived from a cross between AKR/J and SWR/J mice. AKR/J mice are sensitive to dietary obesity when fed a high fat diet while SWR/J mice are resistant. Intercrosses between these strains segregate the phenotype of sensitivity to dietary obesity. Using an F2 mapping population of 931...
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