Article
Genetics of dietary obesity in AKR/J x SWR/J mice: segregation of the trait and identification of a linked locus on chromosome 4.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 1994
West D B, Waguespack J, York B, Goudey-Lefevre J, Price R A
Abstract excerpt
We describe a new multiple gene mouse model of differential sensitivity to dietary obesity that provides a tool for dissecting the genetic basis for body composition and obesity. AKR/J and SWR/J male mice, as well as male progeny of intercrosses between these strains, were fed a high-fat diet for...
Topics
- Alleles
- Animals
- Body Composition
- Body Weight
- Chromosome Mapping
- Crosses, Genetic
- Diet
- Energy Metabolism
- Female
- Genes, Dominant
- Genetic Linkage
- Male
- Mice
- Mice, Inbred AKR
- Mice, Inbred Strains
- Obesity
- Organ Size
- Species Specificity
