Article
Genetics of obesity in KK mouse and effects of A(y) allele on quantitative regulation.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 1998
Suto J, Matsuura S, Imamura K, Yamanaka H, Sekikawa K
Abstract excerpt
KK mouse is known as a polygenic model for noninsulin-dependent diabetes mellitus with moderate obesity. To identify the quantitative trait loci (QTLs) responsible for the body weight in KK, linkage analysis with 97 microsatellite markers was carried out into 192 F2 progeny, comprising 93 mice wi...
Topics
- Agouti Signaling Protein
- Alleles
- Animals
- Body Weight
- Disease Models, Animal
- Female
- Intercellular Signaling Peptides and Proteins
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Obesity
- Proteins
- Quantitative Trait, Heritable
