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Article

Dominant interfering alleles define a role for c-Myb in T-cell development.

Genes & development - 1 Apr 1994

Badiani P, Corbella P, Kioussis D, Marvel J, Weston K

Abstract excerpt

The transcription activator c-Myb is expressed at high levels in immature thymocytes and during T-cell activation and may be a regulator of T-cell differentiation. To investigate the role of c-Myb in T-cell development, we generated transgenic mice in which two dominant interfering Myb alleles, one a competitive inhibitor of DNA binding, and the other, an active repressor comprising the Myb DNA-binding domain...

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PMID: 7926766
DOI: 10.1101/gad.8.7.770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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