Article
Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene.
1 Dec 1991
Abstract excerpt
The nuclear proto-oncogene c-myb is preferentially expressed in lymphohematopoietic cells, in which it plays an important role in the processes of differentiation and proliferation. The mechanism(s) that regulates c-myb expression is not fully understood, although in mouse cells a regulatory mechanism involves a transcriptional block in the first intron. To analyze the contribution of the 5' flanking sequences in...