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Article

c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development.

Molecular biology and evolution - 1 Oct 2008

Lin You-Chin, Kuo Ming-Wei, Yu John, Kuo Huan-Hsien, Lin Ruey-Jen, Lo Wan-Lin, Yu Alice L

Abstract excerpt

Human c-Myb proto-oncogene is highly expressed in hematopoietic progenitors as well as leukemia and certain solid tumor. However, the regulatory mechanisms of its expression and biological functions remain largely unclear. Recently, c-Myb has been shown to be targeted by microRNA-150 (miR-150) which thereby controls B cell differentiation in mice. In this study, we demonstrated that c-Myb is an evolutionary...

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PMID: 18667440
DOI: 10.1093/molbev/msn165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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