Article
Association of slow acetylation profile of NAT2 with breast and gastric cancer risk in Brazil.
Anticancer research - 1 Sept 2013
Fernandes Marianne Rodrigues, de Carvalho Darlen Cardoso, dos Santos Ândrea Kelly Campos Ribeiro, dos Santos Sidney Emanuel Batista, de Assumpção Paulo Pimentel, Burbano Rommel Mario Rodriguez, dos Santos Ney Pereira Carneiro
Abstract excerpt
BACKGROUND: The N-acetyltransferase 2 (NAT2) gene is a marker for the study of interindividual susceptibility to developing neoplasias. The purpose of this study was to verify a possible association between single nucleotide polymomorphisms (SNPs) of NAT2 and the susceptibility to gastric cancer (GC) and breast cancer (BC) in patients from the North region of Brazil. MATERIALS AND METHODS: Five SNPs of the NAT2...
Topics
- Acetylation
- Arylamine N-Acetyltransferase
- Base Sequence
- Brazil
- Breast Neoplasms
- Cohort Studies
- DNA Primers
- Female
- Genetic Predisposition to Disease
- Humans
- Polymorphism, Single Nucleotide
- Risk Factors
- Stomach Neoplasms