Article
HLA class I alleles and responsiveness of melanoma to immunotherapy with interferon-alpha (IFN-alpha) and interleukin-2 (IL-2).
Melanoma research - 1 Jun 1994
Scheibenbogen C, Keilholz U, Mytilineos J, Suciu S, Manasterski M, Hunstein W
Abstract excerpt
MHC-restricted recognition of melanoma cells by cytotoxic T lymphocytes is an important mechanism in vitro. Several HLA alleles can function as restriction elements for melanoma cell recognition. In this study we investigated whether there is a correlation between responsiveness of patients with...
Topics
- Alleles
- Blood Donors
- Drug Administration Schedule
- Genes, MHC Class I
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- Histocompatibility Antigens Class I
- Humans
- Immunotherapy
- Interferon Type I
- Interleukin-2
