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Article

High frequency of allele-specific down-regulation of HLA class I expression in uveal melanoma cell lines.

International journal of cancer - 1 Mar 2000

Hurks H M, Metzelaar-Blok J A, Mulder A, Claas F H, Jager M J

Abstract excerpt

Uveal melanoma is the most common primary intra-ocular tumor in adults and has a high mortality rate due to liver metastases, for which no effective treatment is available. To investigate whether immunotherapy might be feasible in uveal melanoma, the HLA class I surface expression of 6 uveal melanoma cell lines was analyzed by flow cytometry using a broad panel of allele-specific monoclonal antibodies. To...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10699951
DOI: 10.1002/(sici)1097-0215(20000301)85:5<697::aid-ijc16>3.0.co;2-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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