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Article

HLA association with response and toxicity in melanoma patients treated with interleukin 2-based immunotherapy.

Cancer research - 1 Dec 1992

Marincola F M, Venzon D, White D, Rubin J T, Lotze M T, Simonis T B, Balkissoon J, Rosenberg S A, Parkinson D R

Abstract excerpt

Peripheral blood lymphocytes from 146 patients with metastatic melanoma undergoing interleukin 2 (IL-2)-based immunotherapy were characterized for HLA A, B, Cw, DR, DQw, and DRw specificities. Patients had been enrolled into sequential treatment protocols with either IL-2 alone (28) or in combination with tumor-infiltrating lymphocytes (TILs) (86), alpha-interferon (26), lymphokine-activated killer cells (16),...

Topics

Drug Administration Schedule
HLA Antigens
Humans
Immunotherapy
Interleukin-2
Lymphocytes, Tumor-Infiltrating
Melanoma
Phenotype
Prognosis
Remission Induction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1423301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1423301-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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