Article
HLA-B8 association with late-stage melanoma--an immunological lesson?
BMC medicine - 13 Mar 2006
Fensterle Joachim, Trefzer Uwe, Berger Thomas, Andersen Mads Hald, Ugurel Selma, Becker Jürgen C
Abstract excerpt
BACKGROUND: Differences in HLA allele frequencies between the diseased and healthy populations may signify efficient immune responses, a notion that has been successfully tested for infectious diseases or for association with genetic elements involved in a distinct type of immunity. This retrospective study is intended to detect differences in MHC class I carrier frequencies of advanced melanoma patients compared...
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