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Article

Presence of the human leukocyte antigen class II gene DRB1*1101 predicts interferon gamma levels and disease recurrence in melanoma patients.

Annals of surgical oncology - 1 Jul 2002

Lee Jeffrey E, Abdalla Joseph, Porter Geoffrey A, Bradford Loretta, Grimm Elizabeth A, Reveille John D, Mansfield Paul F, Gershenwald Jeffrey E, Ross Merrick I

Abstract excerpt

BACKGROUND: Increased interferon gamma (IFN-gamma) levels are an independent predictor of melanoma recurrence. Human leukocyte antigen (HLA) class II genes can regulate cytokine production; we investigated whether these genes would predict IFN-gamma levels and recurrence in melanoma patients. METHODS: Of 591 patients who presented with localized melanoma, 579 underwent identification of HLA class II alleles; 233...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12095976
DOI: 10.1007/BF02573896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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