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Article

A yeast TCP-1-like protein is required for actin function in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 1994

Vinh D B, Drubin D G

Abstract excerpt

We previously identified the ANC2 gene in a screen for mutations that enhance the defects caused by yeast actin mutations. Here we report that ANC2 is an essential gene that encodes a member of the TCP-1 family. TCP-1-related proteins are subunits of cytosolic heteromeric protein complexes referred to as chaperonins. These complexes can bind to newly synthesized actin and tubulin in vitro and can convert these...

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Source

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Identifiers

PMID: 7916461
DOI: 10.1073/pnas.91.19.9116
PMCID: PMC44758

Genes

BIN2
BIN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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