Article
BIM1 encodes a microtubule-binding protein in yeast.
Molecular biology of the cell - 1 Dec 1997
Schwartz K, Richards K, Botstein D
Abstract excerpt
A previously uncharacterized yeast gene (YER016w) that we have named BIM1 (binding to microtubules) was obtained from a two-hybrid screen of a yeast cDNA library using as bait the entire coding sequence of TUB1 (encoding alpha-tubulin). Deletion of BIM1 results in a strong bilateral karyogamy defect, hypersensitivity to benomyl, and aberrant spindle behavior, all phenotypes associated with mutations affecting...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.