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Article

Bin3 deletion causes cataracts and increased susceptibility to lymphoma during aging.

Cancer research - 15 Mar 2008

Ramalingam Arivudainambi, Duhadaway James B, Sutanto-Ward Erika, Wang Yan, Dinchuk Joseph, Huang Minzhou, Donover Preston S, Boulden Janette, McNally Lois M, Soler Alejandro P, Muller Alexander J, Duncan Melinda K, Prendergast George C

Abstract excerpt

Bin3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins, which includes the BAR, PCH/F-BAR, and I-BAR adapter proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non-Hodgkin's lymphomas and...

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PMID: 18339847
DOI: 10.1158/0008-5472.CAN-07-6072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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