Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast.

doi:10.1091/mbc.4.5.459

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Article

Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast.

Molecular biology of the cell - 1 May 1993

Adams A E, Cooper J A, Drubin D G

Abstract excerpt

To understand the role of the actin cytoskeleton in cell physiology, and how actin-binding proteins regulate the actin cytoskeleton in vivo, we and others previously identified actin-binding proteins in Saccharomyces cerevisiae and studied the effect of null mutations in the genes for these prote...

Topics

Actin Depolymerizing Factors
Actins
Cytoskeleton
Destrin
Genes, Fungal
Genes, Lethal
Membrane Glycoproteins
Microfilament Proteins
Microscopy, Fluorescence
Mutation
Phenotype
Saccharomyces cerevisiae
Suppression, Genetic

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