Article
Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.
PloS one - 1 Jan 2008
Erlich Rachel L, Fry Rebecca C, Begley Thomas J, Daee Danielle L, Lahue Robert S, Samson Leona D
Abstract excerpt
Yeast strains lacking Anc1, a member of the YEATS protein family, are sensitive to several DNA damaging agents. The YEATS family includes two human genes that are common fusion partners with MLL in human acute leukemias. Anc1 is a member of seven multi-protein complexes involved in transcription, and the damage sensitivity observed in anc1Delta cells is mirrored in strains deleted for some other non-essential...
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