Article
Exclusion of linkage between manic depressive illness and tyrosine hydroxylase and dopamine D2 receptor genes.
Psychiatric genetics - 1 Jan 1994
Ewald H, Mors O, Friedrich U, Flint T, Kruse T
Abstract excerpt
Mutations at the tyrosine hydroxylase or dopamine D2 receptor loci causing manic depressive illness are unlikely in two families reported here. Linkage was excluded for both loci assuming a dominant mode of transmission and for the tyrosine hydroxylase locus also assuming a recessive mode of tran...
Topics
- Alleles
- Base Sequence
- Bipolar Disorder
- Female
- Genetic Linkage
- Genetic Markers
- Humans
- Lod Score
- Male
- Molecular Sequence Data
- Pedigree
- Receptors, Dopamine D2
- Tyrosine 3-Monooxygenase