Article
Linkage of mood disorders with D2, D3 and TH genes: a multicenter study.
Journal of affective disorders - 1 Apr 2000
Serretti A, Macciardi F, Cusin C, Lattuada E, Souery D, Lipp O, Mahieu B, Van Broeckhoven C, Blackwood D, Muir W, Aschauer H N, Heiden A M, Ackenheil M, Fuchshuber S, Raeymaekers P, Verheyen G, Kaneva R, Jablensky A, Papadimitriou G N, Dikeos D G, Stefanis C N, Smeraldi E, Mendlewicz J
Abstract excerpt
BACKGROUND: It has been suggested that the dopaminergic system is involved in the pathophysiology of mood disorders. We conducted a multicenter study of families with mood disorders, to investigate a possible linkage with genes coding for dopamine receptor D2, dopamine receptor D3 and tyrosine hydroxylase (TH). METHODS: Twenty three mood disorder pedigrees collected within the framework of the European...
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