Molecular genetic evidence for heterogeneity in manic depression.

doi:10.1038/325805a0

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Article

Molecular genetic evidence for heterogeneity in manic depression.

Nature - 1 Jan 2000

Hodgkinson S, Sherrington R, Gurling H, Marchbanks R, Reeders S, Mallet J, McInnis M, Petursson H, Brynjolfsson J

Abstract excerpt

Manic depression is a severe cyclic mental illness that can be unipolar or bipolar and has a lifetime risk of approximately 7 per 1,000 in most populations. Families with multiple cases of manic depression have been described that are compatible with both autosomal dominant and X-linked modes of...

Topics

Bipolar Disorder
Christianity
Chromosomes, Human, Pair 11
DNA
Depressive Disorder
Ethnicity
Genetic Linkage
Genetic Markers
Humans
Iceland
Mutation
Nucleic Acid Hybridization
Pedigree
Pennsylvania
Polymorphism, Restriction Fragment Length

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Open in PubMed

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PMID: 2881210
DOI: 10.1038/325805a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2881210-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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