Article
No association between dopamine D1, D2, and D3 receptor genes and manic-depressive illness.
Biological psychiatry - 1 Oct 1998
Savoye C, Laurent C, Amadeo S, Gheysen F, Leboyer M, Lejeune J, Zarifian E, Mallet J
Abstract excerpt
BACKGROUND: The dopaminergic receptor genes are candidate genes for manic-depressive illness (MDI). To test this putative involvement we used a case-control study on samples from the native population of the northwest part of France. METHODS: Fifty patients for D1 and D2, 61 patients for D3, and 86-223 controls were tested. RESULTS: No significant association was found between allelic frequencies or genotype...
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