Article
A linkage study with D5 dopamine and alpha 2C-adrenergic receptor genes in six multiplex bipolar pedigrees.
Psychiatric genetics - 1 Jan 1994
Byerley W, Hoff M, Holik J, Coon H
Abstract excerpt
Six kindreds containing multiple cases of manic-depressive illness were genotyped with highly polymorphic microsatellite polymorphisms for the D5 dopamine and alpha 2C-adrenergic receptor genes. Evidence of linkage was not found assuming either autosomal dominant or recessive transmission. The non-parametric sib pair test did not yield evidence of linkage.
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