A linkage study with D5 dopamine and alpha 2C-adrenergic receptor genes in six multiplex bipolar pedigrees.

doi:10.1097/00041444-199400430-00001

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Article

A linkage study with D5 dopamine and alpha 2C-adrenergic receptor genes in six multiplex bipolar pedigrees.

Psychiatric genetics - 1 Jan 1994

Byerley W, Hoff M, Holik J, Coon H

Abstract excerpt

Six kindreds containing multiple cases of manic-depressive illness were genotyped with highly polymorphic microsatellite polymorphisms for the D5 dopamine and alpha 2C-adrenergic receptor genes. Evidence of linkage was not found assuming either autosomal dominant or recessive transmission. The no...

Topics

Alleles
Bipolar Disorder
Genetic Linkage
Genetic Markers
Humans
Lod Score
Nuclear Family
Pedigree
Receptors, Adrenergic, alpha-2
Receptors, Dopamine
Receptors, Dopamine D1
Receptors, Dopamine D5
Regression Analysis

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