Article
The Drosophila trithorax protein binds to specific chromosomal sites and is co-localized with Polycomb at many sites.
The EMBO journal - 1 May 1995
Chinwalla V, Jane E P, Harte P J
Abstract excerpt
trithorax is required to stably maintain homeotic gene expression patterns established during embryogenesis by the action of the transiently expressed products of the segmentation genes. The large trithorax proteins contain a number of highly conserved novel motifs, some of which have been hypothesized to interact directly with specific DNA sequences in their target genes. Using antibodies directed against...
Topics
- Animals
- Binding Sites
- Chromosomes
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression
- Genes, Homeobox
- Genes, Insect
- Immunohistochemistry
- Mutation
- Polycomb Repressive Complex 1