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Article

Regulation of DNA synthesis in division-arrested mouse C127 cells permissive for bovine papillomavirus DNA amplification.

Journal of virology - 1 Jul 1994

Alderborn A, Burnett S

Abstract excerpt

Spontaneous amplification of bovine papillomavirus type 1 DNA occurs following a prolonged period of serum starvation of wild-type virus-transformed C127 cell lines and is associated with abundant viral E2 protein synthesis and a concomitant induction of viral oncogene (E5 and E6) expression. We show here that a subpopulation of the permissive cells incorporate bromo-deoxyuridine under conditions of cell growth...

Topics

Animals
Bovine papillomavirus 1
Cell Division
Cell Line, Transformed
Cells, Cultured
Culture Media, Serum-Free
DNA
Gene Amplification
Giant Cells
Ki-67 Antigen
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Proteins

Nuclear Proteins

Oncogene Proteins

Proliferating Cell Nuclear Antigen

Source

Open in PubMed Open full text

Identifiers

PMID: 7911533
DOI: 10.1128/JVI.68.7.4349-4357.1994
PMCID: PMC236358

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7911533-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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