Evidence that the transcriptional trans-activating function of the bovine papillomavirus type 1 E2 gene is not required for viral DNA amplification in division-arrested cells.

doi:10.1099/0022-1317-73-10-2639

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Article

Evidence that the transcriptional trans-activating function of the bovine papillomavirus type 1 E2 gene is not required for viral DNA amplification in division-arrested cells.

The Journal of general virology - 1 Oct 1992

Alderborn A, Jareborg N, Burnett S

Abstract excerpt

Amplification of bovine papillomavirus type 1 (BPV-1) DNA in growth-arrested mouse cell cultures appears to mimic the process of induction of vegetative BPV-1 DNA synthesis in cells of the stratum spinosum in productively infected bovine warts. In both cases, cells permissive for viral DNA amplif...

Topics

Animals
Cattle
Cell Division
Cell Transformation, Viral
Cells, Cultured
DNA-Binding Proteins
Gene Amplification
Genes, Viral
Hot Temperature
Mice
Mutation
Papillomaviridae
Promoter Regions, Genetic
Trans-Activators
Tumor Virus Infections
Viral Proteins

Source

Open in PubMed

Identifiers

PMID: 1328476
DOI: 10.1099/0022-1317-73-10-2639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1328476-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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