Article
Cell cycle control by p53 in normal (3T3) and chemically transformed (Meth A) mouse cells. I. Regulation of p53 expression.
Oncogene - 1 Nov 1990
Steinmeyer K, Maacke H, Deppert W
Abstract excerpt
In addition to controlling the transition of resting normal cells from the G0-state of the cell cycle into S-phase, expression of the cellular protein p53 also seems to be necessary for the proliferation of cycling normal cells in an as yet undefined manner. To further elaborate the role of p53 in growing cells, we analysed p53 expression and its regulation in cells going into, and after release from, growth...
Topics
- Animals
- Cell Cycle
- Cell Division
- Cell Line
- Cell Line, Transformed
- DNA
- Fibroblasts
- Fibrosarcoma
- G1 Phase
- Gene Expression Regulation
- Isoleucine
- Kinetics