Article
Transformed mouse cell lines that consist predominantly of cells maintaining bovine papilloma virus at high copy number.
Virology - 10 Nov 1995
Ravnan J B, Cohen S N
Abstract excerpt
Rare cells that contain large amounts of bovine papilloma virus (BPV) DNA have been observed in populations of BPV-transformed mouse ID13 cells. The viral DNA molecules in these "jackpot cells" have been thought to have switched from the controlled replication typical of latent BPV infection to the uncontrolled "runaway" prelytic replication characteristic of terminal stage infection of bovine epidermal cells. By...
Topics
- Animals
- Bovine papillomavirus 1
- Cell Line, Transformed
- Cell Transformation, Viral
- DNA Replication
- DNA, Viral
- Mice
- Mitosis
- Phenotype
- Plasmids
- Virus Replication
