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Article

Survival and synaptogenesis of hippocampal neurons without NMDA receptor function in culture.

The European journal of neuroscience - 1 Jun 1998

Okabe S, Vicario-Abejón C, Segal M, McKay R D

Abstract excerpt

Physiological and morphological properties of cultured hippocampal neurons were measured to investigate whether NMDA receptors play a role in survival and differentiation. Neurons dissociated from mouse embryos with different NMDAR1 genotypes were grown in culture. Electrophysiological analysis verified the absence of NMDA receptor-mediated currents in neurons taken from homozygous mutant (NR1-/-) embryos. The...

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PMID: 9753105
DOI: 10.1046/j.1460-9568.1998.00233.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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