Article
Survival and synaptogenesis of hippocampal neurons without NMDA receptor function in culture.
The European journal of neuroscience - 1 Jun 1998
Okabe S, Vicario-Abejón C, Segal M, McKay R D
Abstract excerpt
Physiological and morphological properties of cultured hippocampal neurons were measured to investigate whether NMDA receptors play a role in survival and differentiation. Neurons dissociated from mouse embryos with different NMDAR1 genotypes were grown in culture. Electrophysiological analysis v...
Topics
- Animals
- Calbindins
- Cell Survival
- Cells, Cultured
- Dendrites
- Female
- Genotype
- Heterozygote
- Hippocampus
- Male
- Mice
- Mice, Inbred Strains
- Microtubule-Associated Proteins
- Mutation
- Neurons
- Presynaptic Terminals
- Receptors, N-Methyl-D-Aspartate
- S100 Calcium Binding Protein G