Article
Diversity of multidrug resistance in mammalian cells.
The Journal of biological chemistry - 25 Feb 1994
Devine S E, Melera P W
Abstract excerpt
Mammalian cells displaying the multidrug resistance (mdr) phenotype are refractory to the toxic effects of a group of unrelated natural product drugs, many of which are used for cancer chemotherapy. The pattern of cross-resistance can be extremely variable among independently selected cell lines,...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Animals
- Base Sequence
- Carrier Proteins
- Cell Line
- Colchicine
- Cricetinae
- Cricetulus
- DNA Primers
- DNA, Complementary
- Dactinomycin
- Daunorubicin
- Drug Resistance
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Phenotype
- Transfection