Article
[Multiple drug resistance--theoretical and clinical aspects].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke - 10 Feb 1992
Hofsli E
Abstract excerpt
A major problem in the treatment of cancer is clinical resistance to chemotherapeutic drugs. Multi-drug resistance (MDR) is a well-studied experimental phenomenon which seems to play an important role in clinical resistance to drugs. Tumour cells selected for resistance to a "natural product" anticancer drug display crossresistance to a variety of structurally and functionally unrelated anticancer drugs. Such...
Topics
- Antineoplastic Agents
- Drug Resistance
- Humans
- Membrane Glycoproteins
- Phenotype