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Article

Multiple drug-resistance in variant of a human non-small cell lung carcinoma cell line, DLKP-A.

Cytotechnology - 1 Jan 1992

Clynes M, Redmond A, Moran E, Gilvarry U

Abstract excerpt

A 300-fold adriamycin resistant variant (DLKP-A) of the human lung squamous cell carcinoma line DLKP was established by stepwise selection in increasing concentrations of adriamycin. Different levels of cross-resistance were observed towards VP-16, VM-26, colchicine, vincristine and, somewhat unexpectedly, cis-platin. Resistance was stable for at least 3 months in culture in the absence of drug. P-glycoprotein...

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PMID: 1369413
DOI: 10.1007/BF00376102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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