Article
Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.
Lancet (London, England) - 29 Jan 1994
Heagerty A H, Fitzgerald D, Smith A, Bowers B, Jones P, Fryer A A, Zhao L, Alldersea J, Strange R C
Abstract excerpt
Multiple allelism at loci encoding detoxicating enzymes is associated with cancer risk. We have studied genetic variation at the glutathione S-transferase GSTM1 locus to see whether phenotypes confer altered susceptibility to basal cell carcinoma (BCC), squamous cell carcinoma (SCC), malignant me...
Topics
- Aged
- Alleles
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Case-Control Studies
- Disease Susceptibility
- Female
- Gene Frequency
- Genetic Complementation Test
- Genetic Variation
- Glutathione Transferase
- Heterozygote
- Homozygote
- Humans
- Male
- Melanoma
- Neoplasms, Multiple Primary
- Phenotype