Article
Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.
Lancet (London, England) - 29 Jan 1994
Heagerty A H, Fitzgerald D, Smith A, Bowers B, Jones P, Fryer A A, Zhao L, Alldersea J, Strange R C
Abstract excerpt
Multiple allelism at loci encoding detoxicating enzymes is associated with cancer risk. We have studied genetic variation at the glutathione S-transferase GSTM1 locus to see whether phenotypes confer altered susceptibility to basal cell carcinoma (BCC), squamous cell carcinoma (SCC), malignant melanoma (MM), or multiple skin tumours of different histological types. The frequency of GSTM1 null in cases and...
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