Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deficiency of glutathione S-transferases T1 and M1 as heritable factors of increased cutaneous UV sensitivity.

The Journal of investigative dermatology - 1 Feb 1997

Kerb R, Brockmöller J, Reum T, Roots I

Abstract excerpt

Glutathione S-transferases (GSTs) play a primary role in cellular defense against electrophilic chemical species and radical oxygen species. Because free radical attack is one mechanism of UV irradiation-caused skin damage, we investigated whether genetic variation at the GST loci GST T1 and GST M1 influences individual UVB sensitivity. In a double-blind clinical trial, 50 healthy volunteers were evaluated for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatitis
Share to Double-Blind Method
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Heterozygote

Share to Ultraviolet Rays

Source

Identifiers

PMID: 9008240
DOI: 10.1111/1523-1747.ep12335337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deficiency of glutathione S-transferases T1 and M1 as heritable factors of increased cutaneous UV sensitivity.PMID 9008240Read ↗

Influence of GSTT1 and GSTM1 genotypes on sunburn sensitivity.Semantic proximity Read ↗

Glutathione S-transferase M1 (GSTM1) genotype but not GSTT1 or MC1R genotype influences erythemal sensitivity to narrow band (TL-01) UVB phototherapy.Semantic proximity Read ↗

Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy.Semantic proximity Read ↗

Variations of the melanocortin-1 receptor and the glutathione-S transferase T1 and M1 genes in cutaneous malignant melanoma.Semantic proximity Read ↗

Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.Semantic proximity Read ↗

Glutathione S-transferase M1/T1 genotype and melanoma in a Southern Italian population: a case-control study.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms: influence on susceptibility to cancer.Semantic proximity Read ↗

Interaction of glutathione S-transferase M1 and T1 genotypes and malignant melanoma.Semantic proximity Read ↗

Glutathione S-transferase M1 null genotype, household pesticides exposure and cutaneous melanoma.Semantic proximity Read ↗

Genetic susceptibility to environmental carcinogenesis in Slovenian melanoma patients.Semantic proximity Read ↗

Genetic risk score and acute skin toxicity after breast radiation therapy.Semantic proximity Read ↗

The GSTM1 null genotype confers an increased risk for solar keratosis development in an Australian Caucasian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.