Article
Phenotype of glutathione S-transferase Mu (GSTM1) and susceptibility to malignant melanoma. MMM group. Multidisciplinary Malignant Melanoma Group.
British journal of cancer - 1 Aug 1995
Lafuente A, Molina R, Palou J, Castel T, Moral A, Trias M
Abstract excerpt
The isoenzyme Mu of glutathione S-transferase (GSTM1) is dominantly inherited, and the prevalence of this isoenzyme in the population is about 60%. The lack of GSTM1 has been linked with cancer risk. The frequency of the phenotypes of this isoenzyme in melanoma (MM) patients (n = 197) is reported...
Topics
- Adult
- Aged
- Antioxidants
- Female
- Glutathione Transferase
- Humans
- Isoenzymes
- Male
- Melanoma
- Middle Aged
- Neoplasms, Radiation-Induced
- Phenotype
- Reactive Oxygen Species
- Reference Values
- Risk Factors
- Ultraviolet Rays