Glutathione S-transferase GSTM1 null genotype is not overrepresented in Australian patients with nevoid basal cell carcinoma syndrome or sporadic melanoma.

doi:10.1093/carcin/16.8.2003

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Article

Glutathione S-transferase GSTM1 null genotype is not overrepresented in Australian patients with nevoid basal cell carcinoma syndrome or sporadic melanoma.

Carcinogenesis - 1 Aug 1995

Shanley S M, Chenevix-Trench G, Palmer J, Hayward N

Abstract excerpt

The GSTM1 gene on chromosome 1p encodes the carcinogen-detoxification enzyme, glutathione S-transferase (mu subclass). The homozygous null genotype at this locus has been associated with increased susceptibility to malignancy, including some skin cancers. One hundred and twenty-four Australian pa...

Topics

Carcinoma, Basal Cell
Genotype
Glutathione Transferase
Humans
Melanoma
Skin Neoplasms

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