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Article

Detoxifying enzyme genotypes and susceptibility to cutaneous malignancy.

The British journal of dermatology - 1 Jan 2000

Lear J T, Smith A G, Strange R C, Fryer A A

Abstract excerpt

While ultraviolet (UV) exposure is thought to be a major risk factor for basal cell carcinoma (BCC) and squamous cell carcinoma, more recent research has focused on genetic factors predisposing to these cancers. UV constitutes an oxidative stress with generation of free radicals, leading to lipid and DNA damage and gene mutation. It could therefore be hypothesized that individual ability to deal with these...

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Share to Carcinoma, Basal Cell
Share to Cytochrome P-450 CYP1A1
Share to DNA Repair

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Glutathione Transferase

Share to Oxidative Stress

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 10651688
DOI: 10.1046/j.1365-2133.2000.03339.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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