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Article

Glutathione S-transferase and CYP1A1 gene polymorphisms and non-melanoma skin cancer risk in Italian transplanted patients.

Experimental dermatology - 1 Dec 2006

Lira Macarena Gomez, Provezza Lisa, Malerba Giovanni, Naldi Luigi, Remuzzi Giuseppe, Boschiero Luigino, Forni Alberto, Rugiu Carlo, Piaserico Stefano, Alaibac Mauro, Turco Alberto, Girolomoni Giampiero, Tessari Gianpaolo

Abstract excerpt

Solid organ transplant recipients are at higher risk of non-melanoma skin cancer (NMSC), especially basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Genetic alterations in the production of detoxifying enzymes such as glutathione S-transferase (GST) and CYP1A1 may enhance this risk. We investigated the frequency of GST genotypes (GSTM1, GSTM3, GSTT1 and GSTP1) and CYP1A1 in 239 transplant recipients:...

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Source

Identifiers

PMID: 17083362
DOI: 10.1111/j.1600-0625.2006.00500.x

Genes

GSTM1
GSTP1
GSTM3
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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