Article
Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione S-transferase GSTM1 genotypes, skin type and male gender.
British journal of cancer - 1 Jan 1996
Heagerty A, Smith A, English J, Lear J, Perkins W, Bowers B, Jones P, Gilford J, Alldersea J, Fryer A, Strange R C
Abstract excerpt
The factors that determine development of single and multiple primary cutaneous basal cell carcinomas (BCCs) are unclear. We describe a case-control study firstly, to examine the influence of allelism at the glutathione S-transferase GSTM1 and GSTT1 and cytochrome P450 CYP2D6 loci on susceptibili...
Topics
- Aged
- Alleles
- Carcinoma, Basal Cell
- Case-Control Studies
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Disease Susceptibility
- Female
- Genotype
- Glutathione Transferase
- Humans
- Isoenzymes
- Male
- Mixed Function Oxygenases