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Article

Influence of the glutathione s-transferase gene polymorphisms on the susceptibility to basal cell skin carcinoma.

Revista medica de Chile - 1 Mar 2007

Leite Janaína L, Morari Elaine C, Granja Fabiana, Campos Gabriela M, Guilhen Ana C T, Ward Laura S

Abstract excerpt

BACKGROUND: The identification of groups at high risk is fundamental to determine preventive strategies for skin cancer. Destructive reactive oxygen species produced by UVA or chemical carcinogens are metabolized by a series of enzymes. Polymorphisms of genes encoding for these enzymes may produce defective proteins with a diminished ability to detoxify a wide range of carcinogens. AIMS: To ascertain the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 17505575
DOI: 10.4067/s0034-98872007000300004

Genes

GSTM1
GSTT1
GSTO2
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Influence of the glutathione s-transferase gene polymorphisms on the susceptibility to basal cell skin carcinoma.PMID 17505575Read ↗

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Effect of GSTM1 polymorphism on risks of basal cell carcinoma and squamous cell carcinoma: a meta-analysis.Semantic proximity Read ↗

The glutathione S-transferases: influence of polymorphism on cancer susceptibility.Semantic proximity Read ↗

Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.Semantic proximity Read ↗

An enhanced risk of basal cell carcinoma is associated with particular polymorphisms in the VDR and MTHFR genes.Semantic proximity Read ↗

Investigating the Role of Glutathione S- Transferase Genes, Histopathological and Molecular Subtypes, Gene-Gene Interaction and Its Susceptibility to Breast Carcinoma in Ethnic North- Indian Population.Semantic proximity Read ↗

Association of genetic variants of the vitamin D receptor (VDR) with cutaneous squamous cell carcinomas (SCC) and basal cell carcinomas (BCC): a pilot study in a German population.Semantic proximity Read ↗

Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione S-transferase GSTM1 genotypes, skin type and male gender.Semantic proximity Read ↗

Basal cell carcinoma: from host response and polymorphic variants to tumour suppressor genes.Semantic proximity Read ↗

Effects of GSTT1 and GSTM1 polymorphisms in glutathione levels and breast cancer development in Brazilian patients.Semantic proximity Read ↗

Polymorphism at the glutathione S-transferase locus GSTM3: interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma.Semantic proximity Read ↗

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